Laboratory Toxicokinetics Research Scientist I - Chemical Insights Research Institute

Job Description

We have an exciting opportunity for a Laboratory Toxicokinetics Research Scientist I at UL Research Institutes, based in our Research Triangle Park, office.

The Laboratory Research Scientist I - Toxicokinetics, under general direction, assists in conducting laboratory toxicokinetics research to support CIRI's mission of advancing human and environmental health. This role supports the generation of toxicokinetic data by performing laboratory experiments, generation, analysis, and interpretation of analytical chemistry data, operation and maintenance of analytical chemistry equipment, prepares data summaries and written reports. Works under the supervision of other research scientists to ensure that all laboratory processes and measurements are accurate and technically sound.

UL Research Institutes:

At UL Research Institutes (ULRI), we expand the boundaries of safety science to create a more secure and sustainable world. For more than a century, we have studied the unintended consequences of innovation, designed solutions to mitigate risk and shared our findings with academia, scientists, manufacturers, and policymakers across industries. We identify critical safety and sustainability issues, asking the tough questions because we believe a safer world begins with knowledge.

Build a safer, more secure, and sustainable future with us. Join us and work with our Chemical Insights teams who conduct the research required to produce that knowledge and put into practice.

Chemical Insights Research Institute (CIRI):

The Chemical Insights Research Institute (CIRI) contributes to the protection of public health and well-being by conducting scientific research. Our research and initiatives let people around the world know what chemicals are in the air we breathe and how they affect human health and the planet. We share our research and knowledge through information and application tools with leaders in the scientific, business, and policy communities to raise awareness of human health risks stemming from emerging technologies. To learn more, visit: chemicalinsights.org/

What you'll learn and achieve:

As the Laboratory Toxicokinetics Research Scientist I, you will play a key role in the rapid growth of UL as you:

• Supports research initiatives by performing in vitro laboratory experiments measuring important toxicokinetic processes.

• Performs laboratory experiments including cell culture and handling of human tissues such as plasma and primary hepatocytes.

• Operate and maintain analytical instrumentation such as liquid chromatography (LC), gas chromatography (GC), and mass spectrometry (MS) under established protocols.

• Follow laboratory procedures, standard operating protocols, and organization safety and health requirements.

• Apply quality control and quality assurance measures to ensure accuracy and reproducibility of results.

• Assist in the development and validation of laboratory and analytical chemistry methods.

• Manage sample handling, documentation, and chain-of-custody records.

• Prepare laboratory reagents and calibration solutions for analysis and collect samples (when necessary).

• Support preparation of scientific reports, presentations, grant applications, and peer-reviewed publications.

• Perform basic maintenance of designated test equipment and laboratory and coordinate repairs.

• Monitor laboratory inventory of chemicals, cell culture supplies, and reagents to ensure supplies are readily available and in stock.

• Operate with minimal supervision within defined limits of responsibility and observe good laboratory practices.

• Perform other duties as directed.

What you'll experience working at UL Research Institutes: We have pursued our mission of working for a safer, more secure, and sustainable world for nearly 130 years, embedding conscientious stewardship into everything we do.

• People: Our people make us special. You'll work with a diverse team of experts respected for their independence and transparency and build a network, because our approach is collaborative. We collaborate across disciplines, organizations, and geographies to build the global scientific response that today's global challenges require.

• Interesting work: Every day is different for us here. We see what's on the horizon and use our expertise to build the foundations of a safer future. You'll have the opportunity to push the boundaries of human understanding as part of a team working to advance the public good.

• Grow and achieve: We learn, work, and grow together through targeted development, reward, and recognition programs.

• Values. Four core values guide our work: collaboration, respect, integrity, and beneficence. By living our values, we inspire the trust essential to fulfilling our mission and foster the partnerships that enable us to pursue a beneficent future in which we all can thrive.

• Total Rewards: All employees at UL Research Institutes are eligible for bonus compensation. We offer comprehensive medical, dental, vision, and life insurance plans and a generous 401k matching structure of up to 5% of eligible pay. Moreover, we invest an additional 4% into your retirement saving fund after your first year of continuous employment. Depending on your role, you may be able to discuss flexible working arrangements with your manager. We also provide employees with paid time off, including vacation, holiday, sick, and volunteer days.

What makes you a great fit:

While no one candidate will embody every quality, the successful candidate will bring many of the following professional competencies and personal attributes:

• Demonstrated general knowledge of cell culture, chemistry, analytical chemistry, and associated techniques.

• Experience in in vitro assays for absorption, distribution, metabolism, and/or excretion (ADME) properties.

• Demonstrated ability to maintain science based academic and applied knowledge and skills.

• Excellent communication skills required.

• Basic data analysis skills.

• Ability to collaborate with peers and work directly with Research Scientists and other team members in order to complete a project from start to finish.

Professional education and experience requirements for the role include:

• Bachelor's degree in chemistry, pharmacology, biology, biochemistry, toxicology, or related field and minimum 3 years of directly related work experience; OR

• Master's degree in chemistry, pharmacology, biology, biochemistry, toxicology, or related field and minimum of 1 year related work experience.

• Demonstrated research experience measuring hepatic clearance and plasma protein binding using in vitro methods.

• Strong knowledge of LCMS and GCMS.

About UL Research Institutes and UL Standards & Engagement

UL Research Institutes and UL Standards & Engagement are nonprofit organizations dedicated to advancing safety science research through the discovery and application of scientific knowledge. We conduct rigorous independent research and analyze safety data, convene experts worldwide to address risks, share knowledge through safety education and public outreach initiatives, and develop standards to guide safe commercialization of evolving technologies. We foster communities of safety, from grassroots initiatives for neighborhoods to summits of world leaders. Our organization employs collaborative and scientific approaches with partners and stakeholders to drive innovation and progress toward improving safety, security, and sustainability, ultimately enhancing societal well-being.

Our affiliate, UL Solutions, stands alongside us in working for a safer and more sustainable world. UL Solutions conducts testing, verification and certification, and provides training and advisory services, along with data-driven reporting and decision-making tools, for customers around the world.

To learn more, visit our websites UL.org and ULSE.org.

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